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By Molly Gries, PT, DPT

Painful periods, heavy bleeding and fertility problems are not typical topics of casual conversation, but did you know that these symptoms can be caused by endometriosis? Endometriosis is a painful disorder in which tissue that normally lines the uterus grows outside the uterus. It is linked to estrogen and is an inflammatory condition that is typically worse during menstrual cycles.1,3 With endometriosis, the endometrial-like tissue acts as endometrial tissue would — it thickens, breaks down and bleeds with each menstrual cycle. But because this tissue has no way to exit your body, it becomes trapped. When endometriosis involves the ovaries, cysts called endometriomas may form. Surrounding tissue can become irritated, eventually developing scar tissue and adhesions — bands of fibrous tissue that can cause pelvic tissues and organs to stick to each other affecting fallopian tubes, ovaries, uterus, and other organs in the pelvic and abdominal cavity including the rectum, bladder, vagina, and intenstines2. Endometriosis can affect 6-10% of women during reproductive age and among those, 35-50% of women experience pain, infertility, or both. Despite the prevalence of endometriosis in women, it is oftentimes underdiagnosed and on average takes 6.7 years to definitive diagnosis.1

What are the symptoms?
The most common symptoms associated with endometriosis are painful periods, excessive cramping during menstrual cycles, abnormal or heavy menstrual flow, pain during intercourse, painful urination and bowel movements, infertility, and other gastrointestinal problems. Sometimes, endometriosis manifests as back pain, pelvic pain, even leg pain – which is why some patients with endometriosis are diagnosed by a physical therapist treating them for musculoskeletal pain. Luckily, most women do not exhibit all these symptoms, and several may have a range of symptoms varying in severity based on amount and location of the disease.1,3

Dysmenorrhea, or painful periods, is one of the most common symptoms for endometriosis. While it is normal to experience mild pain for 1-2 days during your menstrual cycle, this should not interfere with daily activities and only last a few days.2 If you frequently must miss work or school, experience significant pain, nausea and/or vomiting with your period, this is outside of normal, and you should discuss these symptoms further with your healthcare providers. Endometriosis is one of the most common causes of infertility and can be found in 24-50% of women who experience infertility. Oftentimes, infertility associated with endometriosis is temporary.1

What causes endometriosis?
While there are many hypotheses, dating back to the 1920s, there is no unifying theory about the root cause of endometriosis. The most common theory is that uterine tissue, endometrium, moves up the fallopian tubes and into the reproductive organs or abdominal cavity during menstruation. This then causes an inflammatory response by white blood cells called macrophages. It is common for endometrium to move into the fallopian tubes and abdominal cavity, most of the time the tissue does not implant onto the tissues and is simply reabsorbed into the body. The reason behind the implantation of the tissue cells is highly debated, however it does seem associated with genetic predisposition, hormonal influences of estrogen and progesterone and general inflammation.1

How is it diagnosed?
Endometriosis is slow to diagnose partly due to the best diagnostic test being an exploratory laparoscopy to look for endometrial lesions and adhesion. MRIs, ultrasound, and pelvic exams may also be used during diagnosis. Frequently, history taking and discussing symptoms with your healthcare provider is the first step to diagnosis and management. There are 4 stages of endometriosis ranging from mild to severe and are dependent on the number of lesions, location, and amount of blockage of the fallopian tubes. However, the amount of disease and severity of symptoms is not always correlated.3

What can you do?
The first step to getting treatment is taking to your healthcare provider about your painful periods and the trying to identify the root cause of your symptoms. Often, the first step is starting with pain management with use NSAIDS, relaxation techniques, heat, and other conservative measures. Frequently, general stretching and yoga can help with pain management. Other treatments include hormone therapy, laparoscopy for removal of lesions, fertility treatment and hysterectomy. Seeking help from a pelvic floor physical therapist can help with pain management, teaching exercises and stretches and working with coordinating pelvic floor and core muscles to help with symptom management. Physical therapy is a good fit for all disease management, including conservative care, pre- and post-operatively.2,3
Painful periods, painful intercourse and heavy menstrual cycles are outside of the norm. If your period is causing you to miss work or school on a regular basis, endometriosis may be the cause.2 Working with a physical therapist that specializes in pelvic heath can help you with pain management and vastly improve your quality of life. Your physical therapist can also refer you to the appropriate medical provider that can evaluate you for pain relieving medications, hormone therapy, laparoscopy, or in rare circumstances, hysterectomy.

References
1. Burney, R. O., & Giudice, L. C. (2012). Pathogenesis and pathophysiology of endometriosis. Fertility and Sterility, 98(3), 511–519. https://doi.org/10.1016/j.fertnstert.2012.06.029
2. Endometriosis. Johns Hopkins Medicine. (n.d.). https://www.hopkinsmedicine.org/health/conditions-and-diseases/endometriosis.
3. Mayo Foundation for Medical Education and Research. (2018, July 24). Endometriosis. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/endometriosis/diagnosis-treatment/drc-20354661.

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